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It's all connected – Thyroid, Prostate, Testosterone and Vitamin A.

It’s all connected! Thyroid hormone, Testosterone, Prostate Cancer and Vitamin A.

Long Story Short:

  • BCO, the enzyme that makes vitamin A from B-carotene, may also be responsible for making Testosterone.
  • Thyroid hormone controls BCO.
  • Hypothyroid > Slow BCO > Low T > Poor prostate health/Low Libido/Decreased lean muscle

A study testing mice found that when mice lacked an enzyme (BCO) which converts beta-carotene to vitamin A (retinol) they had lower Testosterone levels and delayed prostate growth.

What is interesting is this enzyme, BCO, is activated by Thyroid hormones. When I see a patient with low T (guy or gal) I first look to their thyroid health. If Thyroid levels are low their T production can also drop. *Interesting note: People with hypothyroidism sometimes gain an orange tint because they have a build-up of beta carotene (the stuff found in carrots)

It is a misconception that testosterone causes prostate cancer. In fact low T early in life may increase the risk of prostate cancer later on in life.

Bottom Line:


Make sure your thyroid is function is optimal (not just OK!) for the sake of your testosterone and prostate health!

 

Reference:

  1. Joshua W. Smith, Nikki A. Ford, Jennifer M. Thomas-Ahner, Nancy E. Moran, Eric C. Bolton, Matthew A. Wallig, Steven K. Clinton, John W. Erdman. Mice lacking β-carotene-15,15’-dioxygenase exhibit reduced serum testosterone, prostatic androgen receptor signaling, and prostatic cellular proliferation. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, 2016; 311 (6): R1135 DOI: 10.1152/ajpregu.00261.2016
  2. Sciencedaily.com
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